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Full-length human growth hormone represents the central mediator of this axis and is commonly used in research to examine direct growth hormone receptor activation and downstream signaling networks such as JAK2/STAT pathways

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[DOI] [PMC free article] [PubMed] [Google Scholar] Okada M, Kikuchi T, Okamura T, Ikoma Y, Tsuji AB, Wakizaka H, Kamakura T, Aoki I, Zhang MR, Kato K