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Overproduction of ROS One hallmark feature of IBD is the overproduction of ROS, which causes dysregulation of signal transduction, an inflammatory response, and DNA damage, all of which contribute to the progression and deterioration of the disease (27)
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The mechanism behind these gastrointestinal symptoms is believed to be related to the way semaglutide affects the gut hormones that regulate appetite and digestion, leading to a slowing of gastric emptying and increased satiety
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