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Frontiers | Phytic acid attenuates acetaminophen-induced hepatotoxicity via modulating iron-mediated oxidative stress and SIRT-1 expression in mice
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The supply pathway involves the export of GSH from astrocytes via the multidrug‐resistance protein 1 (Mrp1), extracellular processing of GSH by astrocytic γ‐glutamyl transpeptidase (γGT) to the dipeptide cysteinyl‐glycine (CysGly) and hydrolysis of this dipeptide by neuronal aminopeptidase N (ApN) to cysteine (Cys) and glycine (Gly)
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