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When cells are under external stress, iPLA2β can hydrolyze oxidized PUFA-PLs to inhibit p53-induced ferroptosis
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Immune checkpoint inhibitor–related hepatic injury is characterized by prominent T-cell infiltration and macrophage activation, providing a biologic basis for amplified toxicity when a putative offending drug such as moxifloxacin is introduced into an immune-activated milieu (45)
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