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49 Supplementary Material Abbreviations AREs Antioxidant response elements DR Dietary restriction EGF Epidermal growth factor EGFR Epidermal growth factor receptor GST-4 Glutathione S-transferase 4 IIS Insulin/insulin-like growth factor-1 (IGF-1) signaling MAPK Mitogen-activated protein kinase MRJP1 Major royal jelly protein 1 NGM Nematode growth medium Nrf Nuclear factor E2-related factor PLZF Promyelocytic leukemia zinc-finger protein SEM Standard error of the mean Disclosure of potential conflicts of interest No potential conflicts of interest were disclosed

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